Grants Awarded in 2010

Proteolytic Maturation of Perforin: Determining the Requirements for Cytotoxic Function
Kimberly Risma MD, PhD

Cincinnati Children’s Hospital Medical Center – Cincinnati, Ohio USA

Hybrid ImmunoTherapy (ATG/Dexamethasone/Etoposide) for Hemophagocytic Lymphohistiocytosis: The HIT-HLH Trial
Michael Jordan MD

Cincinnati Children’s Hospital Medical Center – Cincinnati, Ohio USA

The Role of BRAF V600E in the Pathogenesis of Langerhans Cell Histiocytosis
Gayane Badalian Very MD, PhD 

Dana-Farber Cancer Institute – Boston, Massachusetts USA

Flow Cytometric and Secretomic Analysis of LCH Lesions
Matthew Collin MD
Institute of Cellular Medicine – Newcastle upon Tyne UK

A Gene Expression Strategy to Identifiy the Cell of Origin in Langerhans Cell Histiocytosis
Carl E. Allen MD, PhD

Texas Children’s Hospital – Houston, Texas USA

Mechanistic Studies of Defects in Lymphocyte Cytotoxicity Underlying HLH
Yenan Bryceson PhD

Center for Infectious Medicine – Stockholm, Sweden

Gene-Expression Profiling of Peripheral Blood Mononuclear Cells in Hemophagocytic Lymphohistiocytosis
Janos Sumegi MD, DSc, PhD

Cincinnati Children’s Hospital Medical Center – Cincinnati, Ohio USA

Identifying Familial Associations in Langerhans Cell Histiocytosis Using the Utah Population Database
Mark Fluchel MD

Primary Children’s Hospital – Salt Lake City, Utah USA

Histiocyte Society Clinical Trials Database System LCH-IV Treatment Protocol Study
Histiocyte Society Executive Board

LCH Study Reference Center – Vienna, Austria

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