Grants Awarded in 2008

 

A Knock-In Mouse Model Mimicking Abnormal Langerhans Cell Trafficking in Langerhans Cell Histiocytosis
Barrett J. Rollins MD, PhD

Dana-Farber Cancer Institute, Harvard Medical School - Boston, Massachusetts USA

Accumulation of Misguided Lymphocytes and Dendritic Cells: A New Model for LCH
Carl E. Allen MD, PhD and Kenneth L. McClain MD, PhD

Texas Children’s Hospital/Baylor College of Medicine - Houston, Texas USA

Revisiting the Candidate Regions for Familial Hemophagocytic Lymphohistiocytosis (FHLH): Loss-of-Function-Screening Search for the Missing Disease Causing Genes
Janos Sumegi MD, PhD
Cincinnati Children’s Hospital Medical Center - Cincinnati, Ohio USA

Proteolytic Maturation of Perforin: Determining the Requirements for Cytotoxic Function in Patients with Hemophagocytic Lymphohistiocytosis
Kimberly Risma MD, PhD

Cincinnati Children’s Hospital Medical Center - Cincinnati, Ohio USA

Mechanisms of Interferon Gamma-Induced Hemophagocytosis
Michael Jordan MD
Cincinnati Children’s Hospital Medical Center - Cincinnati, Ohio USA

Interrogating Disease Mechanisms in a Novel Mouse Model of Hemophagocytosis
Michelle Hermiston MD, PhD

University of California, San Francisco - San Francisco, California USA

Origin of the LCH Cell
Miriam Merad MD, PhD; Matthew Collin MD; Kenneth McClain MD, PhD; Carl Allen MD, PhD

Mount Sinai School of Medicine - New York, New York USA

The Pathogenesis of XLP Due to XIAP Deficiency
Rebecca A. Marsh MD; Jack J. H. Bleesing MD, PhD; Alexandra Filipovich MD

Cincinnati Children’s Hospital Medical Center - Cincinnati, Ohio USA

Histiocyte Society Clinical Trials Database System
 LCH-IV Treatment Protocol Study
LCH Study Reference Center - Vienna, Austria


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