Grants Awarded in 2007


Ganglioside-Induced Defective Granule Exocytosis-Mediated Cytotoxicity in Hemophagocytic Lymphohistiocytosis
Sasa Radoja PhD
Children's National Medical Center – Washington, District of Columbia USA

Lymphocyte Trafficking in Langerhans Cell Histiocytosis
Kenneth McClain MD, PhD and Carl Allen MD, PhD

Texas Children’s Cancer Center/Hematology Service - Houston, Texas USA

Investigations into the Clinical and Molecular Pathogenesis of XIAP Deficiency
Rebecca Marsh MD; Jack J. H. Bleesing MD, PhD; Kimberly Risma MD, PhD; 
Lisa Filipovich MD
Cincinnati Children's Hospital Medical Center – Cincinnati, Ohio USA

A Transgenic Mouse Model Mimicking Abnormal Langerhans Cell Trafficking in Langerhans Cell Histiocytosis
Barrett J. Rollins MD, PhD; Barbara Brandner PhD; Gayane Badalian MD, PhD
Dana-Farber Cancer Institute, Harvard Medical School
Boston, Massachusetts USA

Role of the Granzyme Inhibitor Proteinase Inhibitor-9 (PI-9) in Langerhans Cell Histiocytosis
Carl F. Classen MD
University Childrens Hospital Rostock - Duisburg, Germany

Biomarker Monitoring of Central Nervous System Disease in Langerhans Cell Histiocytosis
Jan-Inge Henter MD, PhD
Karolinska Institutet – Stockholm, Sweden

Mechanisms of IL-17A-Dependent Dendritic Cell Long-Term Survival and Fusion in Langerhans Cell Histiocytosis
Christine Delprat MD, PhD
INSERM – Lyon, France

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