Grants Awarded in 2015

MEK Inhibition in the Therapy of Histiocytic Neoplasms

Omar Abdel-Wahab, MD
Memorial Sloan Kettering Cancer Center, New York, New York USA

Dysregulation of Dendritic Cell Development in Langerhans Cell Histiocytosis II: Langerin Induction and Comparative Gene Expression Studies
Matthew Collin, MD
Newcastle University, Newcastle Upon Tyne, United Kingdom

Deciphering the Underlying Molecular Defects in CTL and NK Cell Cytotoxicity in FHL Patients
Claudio Giraudo, PhD
The Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania USA

Identification of Molecular Mechanisms Underlying Defective Cytotoxic Lymphocyte Function in Chediak-Higashi Syndrome, a Histiocytic Lysosomal Storage Disorder with Immunodeficiency
Konrad Krzewski, PhD
National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland USA

LCH-IV Clinical Trial – Stratum I Patient Registration Reimbursement for North American Institutions
Carlos Rodriguez-Galindo, MD
St. Jude Children's Research Hospital, Memphis, Tennessee USA

The Interplay of NOTCH and MAPK Pathway in LCH
Raphaela Schwentner,  MSc, PhD
Children's Cancer Research Institute, Vienna, Austria

Genetic Dissection of the Exocytic Machinery in Cytotoxic Lymphocytes
Matthias Voss,  PhD
Karolinska Institutet, Stockholm, Sweden

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